GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9457247 | 1 | rs413232 | chr6:167400972 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.17 | 3.76E-7 | Crohn's disease |
| BLCA | cis | rs2275426 | 1 | rs4134386 | chr1:46395089 | CCDC163P | chr1:45960581-45965646:- | -0.35 | -6.56 | 1.75E-10 | Body mass index |
| BLCA | cis | rs1474698 | 1 | rs4140574 | chr6:56099424 | COL21A1 | chr6:55921389-56258892:- | 0.36 | 6.51 | 2.31E-10 | Pulse pressure |
| BLCA | cis | rs1474698 | 1 | rs4140575 | chr6:56099222 | COL21A1 | chr6:55921389-56258892:- | 0.36 | 6.62 | 1.2E-10 | Pulse pressure |
| BLCA | cis | rs9296504 | 1 | rs4144937 | chr6:46628516 | SLC25A27 | chr6:46620679-46645925:+ | -0.25 | -5.03 | 7.39E-7 | QRS complex (Sokolow-Lyon) |
| BLCA | cis | rs2243480 | 1 | rs4145008 | chr7:65647511 | CCT6P1 | chr7:65216092-65228661:+ | -0.35 | -4.71 | 3.52E-6 | Diabetic kidney disease |
| BLCA | cis | rs1401999 | 1 | rs4148575 | chr3:183702275 | ABCC5 | chr3:183637726-183735727:- | -0.2 | -3.96 | 8.97E-5 | Anterior chamber depth |
| BLCA | cis | rs2243480 | 1 | rs4149468 | chr7:65825690 | CCT6P1 | chr7:65216092-65228661:+ | 0.37 | 4.94 | 1.2E-6 | Diabetic kidney disease |
| BLCA | cis | rs9783347 | 1 | rs4150550 | chr11:18350898 | GTF2H1 | chr11:18343816-18388590:+ | 0.32 | 6.12 | 2.28E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150562 | chr11:18354995 | GTF2H1 | chr11:18343816-18388590:+ | 0.32 | 6.05 | 3.38E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150564 | chr11:18355308 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 5.94 | 6.24E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150566 | chr11:18355599 | GTF2H1 | chr11:18343816-18388590:+ | 0.32 | 6.05 | 3.48E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150575 | chr11:18356466 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 6.02 | 4.03E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150579 | chr11:18357180 | GTF2H1 | chr11:18343816-18388590:+ | -0.32 | -6.02 | 4.01E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150610 | chr11:18364140 | GTF2H1 | chr11:18343816-18388590:+ | 0.3 | 5.73 | 1.99E-8 | Pancreatic cancer |